Establishment of Social Skills Training Group in Adolescents With Autism Spectrum Disorder and Effectiveness Analysis

National Taiwan University Hospital1 site in 1 country120 target enrollmentJanuary 1, 2022

ConditionsAutism Spectrum Disorder

Overview

Phase: N/A
Intervention: Not specified
Conditions: Autism Spectrum Disorder
Sponsor: National Taiwan University Hospital
Enrollment: 120
Locations: 1
Primary Endpoint: Autism Diagnostic Interview-Revised (ADI-R)
Status: Recruiting
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Autism spectrum disorders (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction across multiple contexts, and the presence of restricted, repetitive behavior and interests, affecting 1 in 68 children. Although atypical social deficits onset in early childhood, their social relationships with peers may remain a challenge or even worsen for individuals with ASD throughout the school years and beyond, as social contexts increase in complexity and pose higher social expectations.

Registry

clinicaltrials.gov

Start Date

January 1, 2022

End Date

July 12, 2027

Last Updated

2 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

National Taiwan University Hospital

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•aged 11-20 years, currently enrolled in school between the sixth grade of elementary school and the third year of high school
•with a clinical diagnosis of ASD from a licensed mental health or medical professional based on DSM-5
•experiencing social difficulties as reported by parents in a structured intake interview
•scored ≧ 26 on the caregiver-reported Autism Spectrum Quotient (AQ), indicating clinical impairment associated with ASD
•demonstrating verbal fluency in Chinese
•with a full-scale IQ \> 70 on WAIS-IV
•with motivation to participate in the intervention;
•with a caregiver who was fluent in Chinese and willing to participate as a social coach in the study.

Exclusion Criteria

•a history of major mental illness (e.g., bipolar affective disorder, schizophrenia, or psychosis) or neurological diseases that might hinder participation in the treatment
•visual impairment and/or hearing impairment that would preclude participation in group-based social activities.

Outcomes

Primary Outcomes

Autism Diagnostic Interview-Revised (ADI-R)

Time Frame: 7 weeks

Interview with caregiver of autistic participants. Total of 93 items coding from 1 to 9. Higher the score, worse the syptom

The Autism Diagnostic Observation Schedule (ADOS)

Time Frame: 7 weeks

Observe the autistic participant during the interview. the examinee's condition is classified as autism spectrum if the combined score across two domains of social interaction and communication is ≥7, and as autism if the combined score is ≥12. In Module 2, a combined score of ≥8 corresponds to autism spectrum, and a combined score of ≥12 corresponds to autism

Friendship Quality Scale (FQS)

Time Frame: 7 weeks

23 questions scoring from 1 to 5. Higher the score, better the quality of friendship

The Assessing Emotions Scale (AES)

Time Frame: 7 weeks

score range from 33 to 165. higher the score, better the emotional intelligence

Social Responsiveness Scale (SRS)

Time Frame: 7 weeks

65 questions range from 1 to 4. higher the score, worse the symptom.

Friendship Questionnaire (FQ)

Time Frame: 7 weeks

score from 0 to 135. higher the score, the more enjoyment of friendship