The VIRTUE study: Can virtual reality games help people with cognitive impairment following a stroke to regain the ability to perform daily activities?

Phase 2

Completed

• Conditions: Cognitive impairment following a stroke; Nervous System Diseases

• Registration Number: ISRCTN16608742
• Lead Sponsor: Countess of Chester NHS Foundation Trust

Brief Summary

2022 Results article in https://doi.org/10.1109/TNSRE.2022.3158731 (added 14/03/2022) 2021 Abstract results in https://doi.org/10.1177/23969873211034932 Results abstract European Stroke Organisation Conference 2021 (added 29/03/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-03
• Study Completion: 2020-11-30
• Last Update Posted: 10 April 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Aged over 18 years
2. Have suffered a unilateral stroke (both ischaemic and haemorrhagic as diagnosed by stroke physician) between 1 day to 3 weeks previously
3. No or minor pre-stroke handicap defined by modified Rankin scale score before stroke between 0 and 2
4. MoCA score <26 (out of 30) AND a trained Occupational Therapist has identified that the patient who will benefit from further cognitive therapy

Exclusion Criteria

1. History of dementia before the stroke
2. Unfit/too ill to receive occupational therapy within 3 weeks
3. Visual acuity <6/60
4. History of epilepsy
5. Bilateral arm weakness or cannot use their unaffected arm
6. Not able/willing to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Current primary outcome measures as of 04/10/2019:<br> 1. Acceptability of the trial to patients measured using a questionnaire within 1 week following the end of the intervention<br> 2. Cognitive function assessed using Cognitive Assessment of Minnesota (CAM) at baseline, the end of the intervention and 3 months after the end of the intervention<br><br> Previous primary outcome measures:<br> 1. Feasibility and acceptability of VR-based cognitive rehabilitation in patients with cognitive impairment immediately after a stroke<br> 2. Identification of the optimum dosing of VR-based cognitive rehabilitation<br>