The Prevalence and Risk Factors for Thyroid Dysfunction in Pregnant Women in Taiwan
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 2,000
- 试验地点
- 1
- 主要终点
- The prevalence thyroid dysfunction
研究概览
简要总结
The investigators' aim is to enroll around 2000 patients from Taipei, Keelung, Linkou, Chiayi and Kaohsiung CGMH. All participants will receive universal thyroid function screening at 1st trimester, and those who was found to have hyperthyroidism or hypothyroidism will be referred to Endocrine department for further treatment. All participants will be followed at outpatient clinic, and their obstetric visit finding will be recorded. The maternal and neonatal outcomes will be analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women at first trimester (< 14 weeks of gestational age)
排除标准
- 未提供
研究组 & 干预措施
Hyperthyroidism
Elevated fT4, low TSH
干预措施: PTU 50 MG Oral Tablet (Drug)
Hypothyroidism
Elevated TSH, low fT4
干预措施: Levothyroxin (Drug)
结局指标
主要结局
The prevalence thyroid dysfunction
时间窗: 40 weeks
Hypothyroidism: defined as serum TSH \> 2.5U/mL and decreased fT4\*; Hyperthyroidism: defined as fT4 \> normal range\* and TSH undetectable \* Serum free T4 range varies according to trimesters.
次要结局
未报告次要终点