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Clinical Trials/CTRI/2025/11/097442
CTRI/2025/11/097442Not yet recruitingNot Applicable

Incidence of Ventilator-Associated Pneumonia in a Tertiary Care

Dr Chalamani Sai Ravindra Reddy1 site in 1 country80 target enrollmentStarted: December 2, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Enrollment
80
Locations
1
Primary Endpoint
• To determine the incidence rate of ventilator-associated pneumonia (VAP) among patients admitted to the Intensive Care Unit (ICU) in a tertiary care hospital.

Study Overview

Brief Summary

Ventilator-Associated Pneumonia (VAP) is a significant nosocomial infection in patients receiving mechanical ventilation, particularly in intensive care units (ICUs). In tertiary care settings, the incidence of VAP varies widely, typically ranging from 5 to 40 cases per 1,000 ventilator days, depending on local infection control practices, patient comorbidities, and ICU protocols.

Factors contributing to higher incidence in such setups include prolonged mechanical ventilation, invasive procedures, immunosuppression, and inadequate infection control measures. VAP not only increases ICU stay and healthcare costs but is also associated with high morbidity and mortality.

Regular surveillance, adherence to VAP prevention bundles (such as head elevation, daily sedation breaks, oral care with chlorhexidine), and antimicrobial stewardship are crucial to reducing its incidence in tertiary care hospitals.

Study Design

Study Type
Observational

Eligibility Criteria

Ages
15.00 Year(s) to 99.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Both sexes of age more than15 years.
  • On mechanical ventilator more than 48 h.

Exclusion Criteria

  • Those died or developed pneumonia within 48 h.
  • Those who are admitted with pneumonia at the time of admission.

Outcomes

Primary Outcomes

• To determine the incidence rate of ventilator-associated pneumonia (VAP) among patients admitted to the Intensive Care Unit (ICU) in a tertiary care hospital.

Time Frame: 1 year

Secondary Outcomes

  • 1. To identify the common risk factors associated with the development of VAP in mechanically ventilated patients.(2. To study the clinical profile & microbiological spectrum of VAP cases.)

Investigators

Sponsor
Dr Chalamani Sai Ravindra Reddy
Sponsor Class
Other []
Responsible Party
Principal Investigator
Principal Investigator

Chalamani sai ravindra reddy

Dr DY patil medical college

Study Sites (1)

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