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临床试验/NCT00916591
NCT00916591Unknown不适用

Effect of Prokinetic Drugs During the Administration of Enteral Nutrition

Universitair Ziekenhuis Brussel1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2009年9月最近更新:
适应症

试验速览

阶段
不适用
入组人数
60
试验地点
1

研究概览

简要总结

The purpose of this study is to compare the effect of two drugs that can help in the prevention of regurgitation during the administration of enteral nutrition and define which one is the most effective.

详细描述

Two prokinetic drugs (metoclopramide and erythromycin) will be compared during the administration of enteral nutrition in critically ill patients. We would like to know which one is the most effective in preventing regurgitation and risk of aspiration, which is a common complication of enteral nutritional support. This will be evaluated by measuring gastric residue every six hours.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • critically ill patients
  • intubated
  • mechanically ventilated
  • 18 or older age
  • enterally fed

排除标准

  • prokinetic drugs before start study
  • allergy to study medication
  • interactions odf study medication with other drugs
  • recent gastro-intestinal surgery
  • history of esophagectomy or gastrectomy
  • suspicion of gastrointestinal perforation
  • myasthenia gravis
  • liver dysfunction
  • less than 7 days in study
  • gastro- or jejunostomy

研究者

申办方类型
Other

研究点 (1)

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