Clinical Study of Angong Niuhuang Pill and Acupuncture on PSCI Angong Niuhuang Pill Combined With Supervised Pulse Music Electroacupuncture on Cognitive Impairment After Ischemic Stroke
- Conditions
- Post-stroke Cognitive Impairment
- Interventions
- Registration Number
- NCT05731310
- Lead Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Brief Summary
Post stroke cognitive impairment (PSCI) refers to the attainment of cognitive impairment after the clinical event of stroke A range of syndromes that impede diagnostic criteria. Epidemiologically, PSCI is one of the common complications in stroke patients
- Detailed Description
(1) Clinical scale data of cognitive function, daily living ability of PSCI patients integrated with the research of this project using uterine Niu Huang pill combined with examined pulse music electroacupuncture
For analysis, the efficacy of PSCI patients was observed; (2) In depth studies on auditory event-related potentials of PSCI treated by uterine Niu Huang pill combined with examined pulse music electroacupuncture
The changes of serum related nerve growth factor and the relationship between each other in order to enrich / fill our province's research results in this field; (3) In key academic journals
1 high level scientific research paper published.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 65
(1) All were the first stroke, confirmed by head computed tomography (CT) or magnetic resonance imaging (MRI), with vital signs
stable; (2) Those who are conscious and can cooperate with relevant treatment; (3) Montreal Cognitive Assessment Scale (MoCA) score ≤ 24 points; （4）
The course of disease is more than 1 month, and the patient is 40-70 years old.
(1) People with cognitive impairment before onset; (2) There are contraindications of Angong Niuhuang Pill or electroacupuncture treatment;
(3) Complicated with dysfunction of heart, liver, kidney and other important organs; (4) Previous history of cerebral hemorrhage, epilepsy, brain injury, etc; (5) Before onset
Have a history of alcohol and drug dependence; (6) The condition worsens, and new hemorrhagic or infarcted foci appear.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Angong Niuhuang Pill Group Angong Niuhuang Pill Take half an Angong Niuhuang pill every day for 4 weeks Angong Niuhuang pill combined with music electroacupuncture group Angong Niuhuang Pill Take half an Angong Niuhuang pill every day for 4 weeks and Daily music scalp acupuncture treatment
- Primary Outcome Measures
Name Time Method Simple intelligence state examination scale up to 4 weeks MMSE
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
2nd Affiliated Hospital, School of Medicine
🇨🇳Hangzhou, Zhejiang, China