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Clinical Trials/NCT00740701
NCT00740701
Completed
N/A

fMRI and TMS Analysis of Cerebellar Cognitive Function

Johns Hopkins University1 site in 1 country17 target enrollmentApril 2000
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ConditionsCognitive Performance

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cognitive Performance
Sponsor
Johns Hopkins University
Enrollment
17
Locations
1
Primary Endpoint
Behavioral performance (accuracy, or rate of conditioned responses)
Status
Completed
Last Updated
7 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Functional neuroimaging studies have shown that the cerebellum is active during cognitive performance. The investigators hypothesize that stimulation of the cerebellum with transcranial magnetic stimulation will produce brief changes in performance of the task, suggesting that cerebellar activation is necessary for normal cognitive function.

Registry
clinicaltrials.gov
Start Date
April 2000
End Date
January 2005
Last Updated
7 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •19-30 years of age
  • •Informed consent

Exclusion Criteria

  • •History of seizure or a family history of epilepsy
  • •History of stroke
  • •Presence of metal anywhere in the head except the mouth
  • •Presence of cardiac pacemakers
  • •Presence of cochlear implants
  • •Presence of implanted medication pump
  • •History of heart disease
  • •Presence of intracardiac lines
  • •Increased intracranial pressure, such as after infarctions or trauma
  • •Children, or outside of age range

Outcomes

Primary Outcomes

Behavioral performance (accuracy, or rate of conditioned responses)

Time Frame: during computerized task performance (2 hours)

Secondary Outcomes

  • Reaction time(during performance of computerized task (2 hours))

Study Sites (1)

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