MR-guided brachytherapy for ablation of small liver tumors to optimize dose applicatio

Recruiting

• Conditions: C22.0; Liver cell carcinoma

• Registration Number: DRKS00031058
• Lead Sponsor: MU München

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

Clinical indication for local ablative therapy of liver tumors (liver metastases or primary liver tumors). The indication for intervention in this case must be independent of the presented study.
Maximum lesion size 3 cm

Exclusion Criteria

Contraindication to MRI examination

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary endpoint is the detection of non-target radiation exposure of the liver (ratio: non-target volume exposed with target dose to volume of clinical target volume) with propensity score match analysis (criteria: Size of target lesion, tumor entity (or target dose)) to non-target radiation exposure under computed tomographic guidance.

Secondary Outcome Measures

Name	Time	Method
- Local control rate (12 months), <br>- local control rate according to variable focal thermal ablation accessible yes/no (12 months)