NCT04234932Unknown早期 1 期
Short-term Effect of Rho-kinase Inhibitor on Retinal Circulation
适应症
干预措施
相关药物
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Peripapillary capillary perfusion density
研究概览
简要总结
Investigate changes in optical coherence tomography angiography of the optic nerve and macula following topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Normal ocular health
排除标准
- •Females who are or may be pregnant or who are nursing
- •Uncontrolled hypertension
- •Allergy to netarsudil or latanoprost
研究组 & 干预措施
Netarsudil alone
Experimental
Topical application of netarsudil 0.02%
干预措施: Netarsudil Ophthalmic (Drug)
Netarsudil plus latanoprost
Active Comparator
Topical application of netarsudil 0.02% with latanoprost 0.005%
干预措施: Netarsudil Ophthalmic (Drug)
结局指标
主要结局
Peripapillary capillary perfusion density
时间窗: 90 minutes
Mean change in peripapillary capillary perfusion as assessed using optical coherence tomography angiography
次要结局
- Macular capillary perfusion density(90 minutes)
研究者
Richard Trevino, OD, FAAO
Principal Investigator
University of the Incarnate Word
研究点 (1)
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