A multicenter randomized, double-blind, controlled trial for efficacy of YueJu Pills in the treatment of antidepressant

Zhongda Hospital affiliated to Southeast University0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1. Meet the diagnostic criteria for DSM-V or ICD-10 depression;
•2. Aged 18-65 years old;
•3. Patients with mild to moderate depression, Hamilton Depression Scale (24 items) score 35 points = HAMD-24 = 20 points;
•4. In the past 1 week, there have been no Chinese medicines used to treat depression (including Chinese medicine and decoction), western medicine (fluoxetine, escitalopram, venlafaxine, etc.), or in the short term (3-5) Those who have taken the above drugs within days) have been discontinued for more than 7 days;
•5. Willing to accept 42 days of treatment, the subject informed consent, and signed informed consent;
•6. Both are right-handed and emmetropia.

•1. Patients with suicidal depression, the score of the third item of Hamilton Depression Scale = 2 points;
•2. People who are suffering from mental illness other than depression, as well as those caused by external environmental disturbances or traumatic brain injury;
•3. Pregnant or lactating women;
•4. A history of drug allergy;
•5. Under 18 years of age or 65 years of age or older;
•6. Combined with severe primary diseases such as cardiovascular, pulmonary, liver and kidney and hematopoietic system, and patients with severe brain organic diseases and mental illness;
•7. Alcohol and/or psychoactive substances, drug abusers and dependents (including sleeping pills);
•8. Does not meet the inclusion criteria, does not use the drug according to the regulations, can not judge the efficacy or incomplete data, affecting the efficacy and safety judgment;
•9. Unable to understand scale content due to lack of consciousness, language barriers, and intellectual and cultural level;
•10. Left hand;
•11. During the elution period (within 7 days), the patient's depressive symptoms return to a healthy state, that is, the Hamilton Depression Scale score = 20 points after the end of the elution period;
•12. Those who have been depression for more than 2 years.

发起方

Zhongda Hospital affiliated to Southeast University