Chronic postsurgical pain following fractures: a prospective single-center study.

• Conditions: chronic postsurgical pain

• Registration Number: DRKS00011601
• Lead Sponsor: Klinik für Anästhesiologie, Intensiv-, Palliativ- und Schmerzmedizin; Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-13
• Study Completion: 2019-08-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 138

Inclusion Criteria

adult patients (males and females), preoperative written consent for oberservational study and analysis of blood samples, surgery after fracture of upper/ lower extremeties or spine, ability to fully understand nature and puposte of study, ability to meet the study requirements

Exclusion Criteria

< 18 years, insufficient knowledge of German language

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incicende of chronic postsurgical pain following surgical treated bone fractures (upper/ lower extremities and spine) after 3 and 12 months

Secondary Outcome Measures

Name	Time	Method
incidence of CPSP in dependence of type of fracture and type of surgery; incidence of CPSP in dependence of anaesthetic procedures (general anaesthesia or peripheral nerve block or combination of both); assessment of acute posteroperative pain on numerical rating scale (NRS); postoperative presence of PPSB and components of neuropathic pain after 3 and 12 months; influence of pain on daily life activities and quality of life 3 and 12 months later; courses of immunological parameters over 3 and 12 months and their correlation with the presence of neuropathic pain