Clinical Study on Cardiosplenic Concurrent TreatmentMedicine for Improving the Prognosis of Complex Coronary Artery Lesions after Percutaneous Coronary Intervention

Trial Snapshot

No summary available.

•(1) Diagnosed as complex coronary artery lesions, when coronary angiography includes at least one of the following conditions:
•a.bifurcation lesions (side branch diameter>2.0mm);
•b.excessive tortuosity of proximal segment;
•c.severe coronary artery calcification;
•d.chronic total occlusion lesions (>3 months);
•e.left main lesions;
•f.aorto-ostial lesions;
•g.diffuse lesions (>20mm length);
•h.multivessel coronary artery stenosis (=2 two vessels);
•i.extremely angulated lesions(>90°bend);
•j.in-stent restenosis.
•(2) Diagnosed as stable angina of coronary atery disease;
•(3) NYHA function grade I-?;
•(4) Within 2 years after PCI, and at least one coronary stent has been implanted;
•(5) 18 ~ 75 years old;
•(6) Diagnosed as TCM syndrome of heart and spleen deficiency;
•(7) The patient did not take antibiotics, hormones, laxatives, antidiarrheal drugs, and probiotics within 3 months before enrollment;
•(8) Written informed consent is obtained.

•(1) Indication of renal insufficiency with serum creatinine >220umo/l in men or >175umo/l in women;
•(2) Severe liver disease or ALT and AST both 3 times above the upper limit of normal;
•(3) Controlled systolic blood pressure >160 mmHg or diastolic blood pressure >100 mmHg;
•(4) Diabetic patients with random blood glucose = 13.7 mmol/L or glycosylated hemoglobin = 9.5%;
•(5) Women who are pregnant or planning to become pregnant, or who are breastfeeding;
•(6) Severe acute or chronic cerebrovascular disease;
•(7) Malignancies;
•(8) Severe hematopoietic disorders;
•(9) Severe mental illness;
•(10) Inflammatory or malabsorptive intestinal disorders;
•(11) Patients who have participated within the last three months or are participating in other clinical trials;

Sponsor