JPRN-UMIN000004694
Completed
Phase 2
Conversion therapy of Cetuximab plus FOLFIRI followed by Bevacizumab plus mFOLFOX6 in patients with liver metastatic colorectal cancer - N-SOG 04
agoya Surgical Oncology Group0 sites50 target enrollmentDecember 10, 2010
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- agoya Surgical Oncology Group
- Enrollment
- 50
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •(1\)Severe myelosuppression (2\)Diarrhea(watery) (3\)Require treatment of serious infection (4\)Uncontrolled body cavity fluid (5\)Comorbidity or history of interstitial lung disease or pulmonary fibrosis (6\)Severe hypersensitivity (7\)Renal failure or urine protein \>\=\+2 within 1 week before enrollment (8\)Uncontrollable hypertension or diabetes (9\)Significant abnormal ECG or history of cardiovascular disease within 1year (10\)Thrombosis with present or history of thromboembolism within 1year (11\)Intestinal bleeding, ileus, bowel obstruction or peptic ulcer (12\)Perforation of gastrointestinal tract within 1year (13\)Administrated with Aspirin (\>\=325mg/day) or steroid for rheumatoid arthritis and chronic inflammatory disease (14\)Pregnant and lacting woman,woman with suspected pregnancy, and men of the fertility hope (15\)Have anti\-thrombosis drugs within 7days before enrollment (16\)Need to treatment with Atazanavir sulfate (17\)Active multiple cancers (18\)Severe mental illness (19\)Treated continuously with systemic steroids (20\)Any subject judged by the investigator to be unfit for any reason to participate in the study
Outcomes
Primary Outcomes
Not specified
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