NCT00793559
Unknown
Phase 2
Terlipressin Administration in Septic Shock Refractory to Catecholamines Bolus vs. Continuous Drip-Phase II
Overview
- Phase
- Phase 2
- Intervention
- terlipressin
- Conditions
- Septic Shock
- Sponsor
- Assaf-Harofeh Medical Center
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- CI, SVR,HR,BP, noradrenalin administration,renal function
- Last Updated
- 17 years ago
Overview
Brief Summary
terlipressin is given to refractory septic shock patients who do not respond to noradrenalin in Israel and Europe. It is given by bolus injection. we attempt to investigate weather it is better to give it by continuous drip and avoid abrupt changes in BP and heart function
Investigators
Eligibility Criteria
Inclusion Criteria
- •septic shock patients receiving above 0.5 mcg/kg NA
Exclusion Criteria
- •allergy to terlipressin, CHF, IHD, pregnancy
Arms & Interventions
terlipressin bolus
1 mg of terlipressin received one time only
Intervention: terlipressin
terlipressin drip
Intervention: terlipressin
Outcomes
Primary Outcomes
CI, SVR,HR,BP, noradrenalin administration,renal function
Time Frame: 6 mo
Study Sites (1)
Loading locations...
Similar Trials
Recruiting
Phase 2
Terlipressin for Refractory Septic ShockSeptic ShockRefractory ShockNorepinephrine Adverse ReactionNCT04339868Mahidol University130
Unknown
Phase 4
Evaluation of Early Association of Terlipressin and Norepinephrine During Septic Shock; the TerliNor StudySeptic ShockNCT03336814Assistance Publique Hopitaux De Marseille40
Unknown
Not Applicable
Continuos Terlipressin Infusion in Septic ShockSeptic ShockNCT01697410First Affiliated Hospital, Sun Yat-Sen University1,000
Unknown
Not Applicable
The Effect of Terlipressin on Intesitnal Function in Septic Shock PatientsTerlipressinSeptic ShockNCT02306239Liu ZiMeng40
Completed
Phase 2
Terlipressin in Septic Shock in CirrhosisLiver CirrhosisSeptic ShockNCT00628160Hospital Clinic of Barcelona72