Effect of spot urine sodium guided diuretics regimen in patients with acute decompensated heart failure

Phase 1

• Conditions: Acute decompensated heart failure; Acute decompensated heart failure, furosemide, loop diuretic, urine sodium, urine output

• Registration Number: TCTR20231108001
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-11-08
• Study Completion: 2024-06-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1.Age more than 18-year-old with hospital admission with the principal diagnosis of acute decompensated heart failure within 24 hours of the hospital visit.
2.Presence of at least one symptoms and signs of volume overload: orthopnea, paroxysmal nocturnal dyspnea, jugular venous distension, lung crepitation.

Exclusion Criteria

1.Hydrochlorothiazide, acetazolamide, or tolvaptan use within 48 hours prior to the enrollment period
2.Systolic blood pressure < 90 mmHg or mean arterial pressure < 65 mmHg
3.Inotrope or vasopressor usage
4.Glomerular function rate < 30 ml/min/1.73m2
5.Use of renal replacement therapy or ultrafiltration
6.Exposure to intravenous contrast agents anticipated within the next 72 hours
7.Need for invasive mechanical ventilation
8.Concurrent diagnosis of an acute coronary syndrome
9.History of cardiac transplantation and/or ventricular assist device
10.Pregnant or currently breastfeeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified