Experience and report of non-specific symptoms in chronic fatigue syndrome

Withdrawn

• Conditions: functionele syndromen; chronic fatigue syndrome

• Registration Number: NL-OMON34662
• Lead Sponsor: niversiteit Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 72

Inclusion Criteria

Female, non-smoking, age between 20 and 60 years. No medical or psychiatric disorder.
Specific for patientgroup: unexplained chronic fatigue lasting more than 6 months.

Exclusion Criteria

Indication or diagnosis of any medical or psychiatric disorder. Use of systemic medication. Drugs use in month prior to study. Alcohol abuse in month prior to study. Primary sleep disorder that can account for the fatigue complaints. Pregnancy during or in three months before the study. Occurrence of an infection in the week prior to the study. Experience from earlier research shows that about 50 % of potential participants in the chronic fatigue group will be excluded due to use of systemic medication.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary study parameters are: blood plasma CRP-concentrations; self report of<br /><br>negative mood, fatigue, pain complaints and cognitive complaints; pressure pain<br /><br>parameters; and mental effort during a cognitive task.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are Indoleamine 2,3-dioxygenase-mRNA expression and<br /><br>score on a pain catastrophizing questionnaire.</p><br>