Longterm Outcome of Children With Neonatal Intra-Ventricular or Intra-Cranial Hemorrhage (IVH, ICH)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Neonates Premature
- Sponsor
- Laniado Hospital
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- need for surgery related to neonatal hemorrhage
- Status
- Recruiting
- Last Updated
- 9 years ago
Overview
Brief Summary
Intraventricular hemorrhage (IVH) is the most commonly recognized cerebral lesion on ultrasound in extremely preterm infants. Papile classification is commonly used to grade the severity of IVH. Grade III-IV IVH and other lesions noted on ultrasound including periventricular leukomalacia (pvl) porencephaly, and ventriculomegaly are well Documented to be associated with adverse neurodevelopmental outcomes.
However, the true impact of lower-grade IVH on the neurodevelopment of these extreme preterm infants has not been well described.
Also Neurodevelopmental outcome for neonatal non-traumatic Intra Cranial Hemorrhage (ICH) is not well established.
The aim of this study is to look retrospectively at babies with neonatal IVH or ICH and follow their radiological, cognitive, motor and functional outcomes.
The study will focus on postnatal files, and on images performed as part of the child's follow-up during hospitalization and after discharge.
Detailed Description
The study will be performed as a Retrospective chart review with key words : IVH, ICH of babies discharged from Laniado Hospital Neonatal care service or ICU, or being followed in the pediatric neurosurgical clinic and prematurity/neonatology clinic of the hospital. All charts of such children will be included, to review clinical, and radiological available data. Registration of Clinical, Radiological data as presented or submitted by the parents on Neurosurgical neonatology and Neurological Followups will be performed by PI or CI and coded in the data anonymously. Follow up will be performed as clinically indicated without addition of any specific studies due to the research. The endpoints of the study: primary endpoint: 1. How many children needed surgical intervention related to the hemorrhage (ICH, IVH) secondary endpoints: 2. Clinical and functional outcome of children - REGARDING normal schooling, need for assistance in ADL in difference from the parallel normal child. correlation between the type of hemorrhage, clinical data related to gestational age and weight at birth, and outcomes will be performed.
Investigators
Laniado Hospital
Liana.Adani
Laniado Hospital
Eligibility Criteria
Inclusion Criteria
- •newborns or premature babies who suffered intra-cranial or intra-ventricular hemorrhage children who are followed by PI in the neurosurgical clinic in Laniado hospital and suffered from ICH or IVH and were treated elsewhere after birth -
Exclusion Criteria
- •loss to followup within the first year after birth
Outcomes
Primary Outcomes
need for surgery related to neonatal hemorrhage
Time Frame: 3 years
Secondary Outcomes
- normal schooling according to age(6 years)
- need for ADL assistance beyond acceptable per age(6 years)