A clinical trial to study the efficacy of heated humidified high ?flow nasal cannula flow rates of 1L/kg/min and 2L/kg/min in the management of acute bronchiolitis in children admitted to pediatric intensive care unit.
Phase 3
- Conditions
- Health Condition 1: J219- Acute bronchiolitis, unspecified
- Registration Number
- CTRI/2023/08/056192
- Lead Sponsor
- Arathy Wilson P
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All children less than one year, admitted with bronchiolitis and modified TAL score more than 5 initiated on HHHFNC support.
Exclusion Criteria
Children with preexisting cardiac illness, neuromuscular diseases, chronic lung diseases.
Children with orofacial anomalies
Children who are born less than 37 weeks
Children on home NIV
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of treatment failure in each group <br/ ><br>Treatment failure is defined as <br/ ><br>Increase in modified TAL score by 1 <br/ ><br>Hemodynamic instability BP less than 5th percentile <br/ ><br>Altered sensorium GCS less than 13Timepoint: Duration of the ICU stay <br/ ><br>
- Secondary Outcome Measures
Name Time Method Time from randomization to liberation (weaning) from HHHFNC support <br/ ><br>Length of ICU stayTimepoint: Duration of stay