MedPath

Vaginal Infection Study 2

Phase 3
Completed
Conditions
Vaginal Infection
Interventions
Registration Number
NCT00694928
Lead Sponsor
Lumara Health, Inc.
Brief Summary

This study will evaluate the efficacy and safety of a vaginal product compared with that of another vaginal product in the treatment of vaginal infections.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
843
Inclusion Criteria
  • Patients must have a clinical diagnosis of vaginal infection.
  • Patients must be post-menopausal, surgically sterilized or using an acceptable form of birth control.
Exclusion Criteria
  • Patients must not have any other infections
  • May not be pregnant or nursing
  • May not be receiving any other antimicrobial therapies or any medications that would interfere with the outcome of the study.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1clindamycin phosphate/butoconazole nitrateclindamycin phosphate/butoconazole nitrate
2butoconazole nitratebutoconazole nitrate
Primary Outcome Measures
NameTimeMethod
Clinical symptom resolutionbaseline, 7 to 10 days and 21 to 30 days
Secondary Outcome Measures
NameTimeMethod
Yeast Culture for Candidabaseline, 7 to 10 days and 21 to 30 days

Negative Yeast Culture for Candida result=response, Positive Yeast Culture for Candida result=no response

Gram Stain Nugent Scorebaseline, 7 to 10 days and 21 to 30 days

Gram stain Nugent score of less than 4= resolution, Gram stain Nugent score of greater than 4= no resolution

Saline wet mount for clue cellsbaseline, 7 to 10 days and 21 to 30 days

Saline wet mount negative for clue cells=resolution, Saline wet mount positive for clue cells=no resolution

Trial Locations

Locations (73)

Brookwood Ob-GYN, PC/Women's Medical Plaza

🇺🇸

Birmingham, Alabama, United States

Drug Research Analysis Corp

🇺🇸

Montgomery, Alabama, United States

Drug Research and Analysis Corp.

🇺🇸

Montgomery, Alabama, United States

Ob/Gyn Associates

🇺🇸

Jonesboro, Arkansas, United States

The Woman's Clinic, PA

🇺🇸

Little Rock, Arkansas, United States

Peak Health Medical Group

🇺🇸

Los Angeles, California, United States

Women's Health Care at Frost Street

🇺🇸

San Diego, California, United States

Steven Freedman, MD, Inc.

🇺🇸

West Hills, California, United States

Red Rocks OB/GYN

🇺🇸

Lakewood, Colorado, United States

SHE Medical Center

🇺🇸

Hartford, Connecticut, United States

Scroll for more (63 remaining)
Brookwood Ob-GYN, PC/Women's Medical Plaza
🇺🇸Birmingham, Alabama, United States

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.