Can Delta Neutrophil Index Values Predict the Success of Periodontal Treatment in Patients With Periodontitis?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Changes in Delta Neutrophil Index values of periodontal treatment in patients with periodontitis.
研究概览
简要总结
The study included 70 systemically healthy individuals, as a test group of 35 patients with Stage 3, Grade A periodontitis and a control group of 35 individuals with no periodontal disease. Blood samples were taken for the examination of DNI, white blood cells (WBC), immature granulocytes (IG), procalcitonin, C-reactive protein (CRP), lymphocyte count and neutrophil count. For the patients with periodontitis, blood sample assays were repeated 3 months after NSPT.
详细描述
The role of the Delta Neutrophil Index (DNI) in the pathogenesis and follow-up of periodontal disease has not been comprehensively documented. The study included 70 systemically healthy individuals, as a test group of 35 patients with Stage 3, Grade A periodontitis and a control group of 35 individuals with no periodontal disease. Blood samples were taken for the examination of DNI, white blood cells (WBC), immature granulocytes (IG), procalcitonin, C-reactive protein (CRP), lymphocyte count and neutrophil count. For the patients with periodontitis, blood sample assays were repeated 3 months after NSPT.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients diagnosed with periodontitis
- •Patients have more than 20 teeth in the mouth
- •Minimum age 18
- •Maximum age 65
排除标准
- •Patients with any systemic disease
- •Active smokers
- •Pregnant or breastfeeding
- •Patients have used any antibiotic or anti-inflammatory drug in the last 6 months
- •Patients have received any periodontal treatment in the last 6 months.
结局指标
主要结局
Changes in Delta Neutrophil Index values of periodontal treatment in patients with periodontitis.
时间窗: 12 weeks
We expect a decrease in the Delta Neutrophil Index values after non-surgical periodontal treatment.
次要结局
- Neutrophil-lymphocyte ratio (NLR) values after non-surgical periodontal treatment.(12 weeks)
研究者
Eda Cetin Ozdemir
assistant professor
Kahramanmaras Sutcu Imam University