NL-OMON50848CompletedNot Applicable
Postprandial Lipids in IBS and Nutritional Treatment - PLINT study
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Wageningen Universiteit
- Enrollment
- 20
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •-IBS patients that meet the Rome IV criteria + additional criteria specific for
- •the diarrhea-predominant and mixed subtype: IBS-D and IBS-M
- •- Male and female adults, aged 18-70 years;
- •- Having a Body Mass Index (BMI) between 18.5 and 30 kg/m2;
- •- Willing to keep a stable dietary pattern throughout the study.
Exclusion Criteria
- •*Having a disease that may interfere with the outcomes of this study, such as a
- •known autonomic disorder, inflammatory bowel disease, coeliac disease, cancer,
- •dialysis patients, chronic kidney failure, depression or hypothyroidism.
- •* History of intestinal surgery (excluding appendectomy or cholecystectomy) or
- •endometriosis.
- •* Use of medication that can interfere with the study outcomes, including
- •codeine and antibiotics, as judged by the medical supervisor.
- •* Use of anticoagulants (as curcumin has inhibitory effects on platelet
- •aggregation).
- •* Use of prebiotics and/or probiotics (should be stopped 4 weeks before the
- •start of the study) and infrequent use of other supplements dedicated to bowel
- •function improvements. Some supplements are allowed (judged by medical
- •supervisor MD Ben Witteman) but intake should be kept stable during the whole
- •study period.
- •* Having swallowing problems with pills/capsules.
- •* Having a cow*s milk allergy or other food allergies.
- •* If applicable: currently pregnant or breastfeeding, or intending to become
- •pregnant during the study.
- •* Participation in another clinical trial at the same time.
- •* Student or employee working at Food, Health and Consumer Research from Food
- •and Biobased Research, or Department of Human Nutrition & Health, Wageningen
- •University.
- •* Alcohol intake * 14 (women) or * 28 (men) glasses of alcoholic beverages per
- •* Smoking and abuse of illicit drugs, soft drugs, and/or nitrous oxide.
Investigators
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