Effect of Intraoperative Intravenous lidocaine infusion And comparison with the effect of intravenous remifentanil infusion , on postoperative pain after laparoscopic cholecystectomy surgery
Phase 2
- Conditions
- K80.0Acute cholecystitis.Calculus of gallbladder with acute cholecystitis
- Registration Number
- IRCT20141009019470N89
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 81
Inclusion Criteria
ASA I-II
Age 18 to 75 years
Patients Candidate for Laparoscopic Cholecystectomy
Exclusion Criteria
Non-cooperation patients after surgery
Severe physical and mental disorders
Severe bradycardia (heart rate less than 40 times per minute)
Severe bleeding leading to laparotomy
A history of allergies to topical anesthetics and lidocaine and opioids
Chronic use of opioids and nonsteroidal anti-inflammatory drug and alcohol
Pregnancy
History of heart, liver and kidney failure
The heart rate is less than 50 minutes per minute and any block on the ECG
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of pain in recovery. Timepoint: On arrival to recovery and every 15 minutes to 60 minutes in recovery. Method of measurement: NRS.;Severity of pain in the ward. Timepoint: Every one hour up to 6 hours, and then 12 and 24 hours. Method of measurement: NRS.
- Secondary Outcome Measures
Name Time Method Sedation Score. Timepoint: At the arrival to the recovery room. Method of measurement: four-point categorical scale.