Exhaled breath acetone as a predictor of worse prognosis in patients with advanced heart failure

Not Applicable

Completed

• Conditions: Heart failure; Circulatory System

• Registration Number: ISRCTN98990677
• Lead Sponsor: niversidade de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2024-03-01
• Study Start: 2024-03-05
• Last Update Posted: 18 March 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 287

Inclusion Criteria

Patients with decompensated heart failure on inotropic support

Exclusion Criteria

Not meeting the participant inclusion criteria

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Exhaled acetone measured in breath collected in a portable non-invasive device and analyzed using spectrophotometry after reaction with salicylaldehyde at one time point

Secondary Outcome Measures

Name	Time	Method
The following secondary outcomes are measured using medical records during the hospitalization to 6-months follow-up:<br>1. Intensive care unit (ICU) admission<br>2. Need for devices such as an intra-aortic balloon pump, ECMO<br>3. Heart transplant (HT) or left ventricular assist device (LVAD)<br>4. Death or in-hospital HT<br>5. Death or HT<br>6. In-hospital death<br>7. Overall mortality<br><br>