Non-alcoholic, Fiber-enriched Beer and Its Effect on Blood Glucose Concentration

Not Applicable

Not yet recruiting

• Conditions: Blood Glucose Concentration; Glycemic Index; Dietary Fiber; Non-alcoholic Beer

• Registration Number: NCT07131904
• Lead Sponsor: David Faeh

Brief Summary

This study examines how various non-alcoholic beverages affect blood sugar levels.

The beverages are a non-alcoholic, fiber-enriched beer, a conventional non-alcoholic beer, and a sugar solution. Participants drink one of these beverages on different days. Afterwards, a sensor on the upper arm is used to measure the sugar content in the body fluid under the skin over a period of two hours.

The aim is to find out how much blood sugar concentration rises after drinking. This will be used to check whether the non-alcoholic, fiber-enriched beer has a more favorable effect on sugar metabolism than conventional beverages. Participation is voluntary, and the data will be treated confidentially.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-08
• Study Start: 2025-08-12
• Study First Submitted: 2025-08-13
• Study First Submitted QC: 2025-08-13
• Last Update Submitted: 2025-08-13
• Study First Posted: 2025-08-20
• Last Update Posted: 2025-08-20
• Primary Completion: 2025-09-22
• Study Completion: 2025-10-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Healthy adults aged 18-60 years
• Body mass index (BMI) between 18.5 and 29.9 kg/m²
• Signed informed consent

Exclusion Criteria

• Diagnosed diabetes
• Gastrointestinal diseases
• Hormonal or other metabolic diseases
• Allergies or intolerances to beer ingredients
• Professional sports (>10 hours/week of intense exercise)
• Special diets (e.g., low-carb, intermittent fasting)
• Sleep disorders or inability to maintain regular sleep (e.g., shift work)
• Pregnancy or breastfeeding
• Smoking
• Inability to speak German or English
• Problems with alcohol, drug, or medication abuse
• Inability to sign informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Incremental Area Under the Curve (iAUC) for Postprandial Blood Glucose	0-120 minutes after beverage consumption on each test day	Incremental area under the curve for interstitial glucose concentration measured over 120 minutes after beverage consumption. Measurements obtained via continuous glucose monitoring (FreeStyle Libre 3) in a randomized crossover design.

Secondary Outcome Measures

Name	Time	Method
Glycemic Index of Fiber-Enriched Beer (FEB)	0-120 minutes after beverage consumption on each test day	Glycemic index calculated using the incremental area under the curve for blood glucose after consumption of FEB, compared to glucose solution, according to ISO 26642:2010 methodology.