Transjugular Intrahepatic Porto-systemic Shunt (TIPS) with Gore-tex covered stent-graft versus endoscopic treatment for acute bleeding of esophageal varices.

Recruiting

• Conditions: bleeding of esophageal varicose veins; portal hypertension; 10019654

• Registration Number: NL-OMON39467
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 72

Inclusion Criteria

Acute or subacute bleeding of esophageal varices as documented with diagnostic endoscopy.
Initial stabilization, as achieved by using octreotide infusion and endoscopic ligation of the major bleeding vessel, and placement of a Sengstaken tube in patients in whom the former combination treatment fails to stop the bleeding.
Informed consent.

Exclusion Criteria

Serious or untreatable encephalopathy.
Heart failure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Recurrence of bleeding</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Initial technical success in staunching bleeding.<br /><br>Child Pugh classification.<br /><br>Incidence of encephalopathy.<br /><br>Mortality.<br /><br>Medical costs.<br /><br>Non-medical costs.</p><br>