Treatment of Peri-implant Mucositis: Adjunctive Benefit of Glycine Powder Air Polishing Device to Professional Mechanical Biofilm Removal. A Randomized Parallel Arm Clinical Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Peri-implant Mucositis
- Sponsor
- University of Siena
- Enrollment
- 52
- Locations
- 1
- Primary Endpoint
- Bleeding on probing
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The aim of the present study is to evaluate the adjunctive effect of glycine-powder air-polishing (GPAP) to full-mouth ultrasonic debridement (Fm-UD) in the treatment of peri-implant mucositis, and to determine the predictive role of implant and patient-level variables for disease resolution. Both treatments are described in the literature, but few studies are available on their comparison.
Detailed Description
52 patients (132 implants) with peri-implant mucositis were included in this randomized parallel arm clinical study. Following baseline variables assessment, participants received Fm-UD. Implants allocated to the test group (n=64) were additionally treated with GPAP. Clinical outcomes were evaluated at 3 and 12 months following intervention. Complete and partial disease resolution were defined as absence of BoP (DR1) or \<2 BoP+ sites (DR2), respectively.
Investigators
Nicola Discepoli
Professor
University of Siena
Eligibility Criteria
Inclusion Criteria
- •age between 18 and 70 years old;
- •presence of one implant loaded at least one year before;
- •bleeding on probing and/or suppuration of the peri-implant mucosa;
- •pain and/or tenderness of the peri-implant mucosa;
- •good general health conditions.
Exclusion Criteria
- •radiographic bone loss ≥ 2mm;
- •intake of anticoagulants, antiplatelet, antibiotic or cortisone drugs;
- •inability to perform oral hygiene maneuvers.
Outcomes
Primary Outcomes
Bleeding on probing
Time Frame: 12 months
After probing dental and implant sites a dichotomic value (0/1) is assigned for each site. 0: not bleeding site; 1: bleeding site.
Secondary Outcomes
- Probing pocket depth change(12 months)