Comparison of controlled ovarian stimulation with clomiphen citrate HMG(Human menopausal gonadotropin) or clomiphen citrate rFSH(recombinant follicule stimulating hormon) in IUI(Intrauterine Insemination) cycles.

Not Applicable

• Conditions: Condition 1: Unexplained infertility. Condition 2: Male factor infertility.; Female infertility, unspecified; Oligospermia NOS

• Registration Number: IRCT201109163386N4
• Lead Sponsor: Semnan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 142

Inclusion Criteria

history of infertility of more than 1 year; wemon's age between 20 and 40 years old; documentation of normal ovulatory cycles; normal TSH and Prolactin level; normal reproductive hormones in the early follicular phase;patent tubes have been shown by HSG or laparoscopy; normal sperm count, motility and morphology according to the World Health Organization criteria(WHO 1992)in unexplained infertility and total motile sperm count more than 1 million in male factor infertility.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy rate. Timepoint: 7 weeks of gestation. Method of measurement: Fetal heart activity with ultrasound.;Ongoing pregnancy rate. Timepoint: 12 weeks of gestation. Method of measurement: Fetal heart activity with ultrasound.

Secondary Outcome Measures

Name	Time	Method
Mean of follicular size on the day of HCG administration. Timepoint: Day of occurrence of at least one ovarian follicule =16 mm in diameter. Method of measurement: Ultrasound.;Endometrial thickness on the day of HCG administration. Timepoint: Day of occurrence of at least one ovarian follicule =16 mm in diameter. Method of measurement: Ultrasound.;Total dose of gonadotropin. Timepoint: Day of occurrence of at least one ovarian follicule =16 mm in diameter. Method of measurement: Number of vials.;Duration of stimulation with gonadotropin. Timepoint: Day of occurrence of at least one ovarian follicule =16 mm in diameter. Method of measurement: Number of days gonadotropin was administered.;Number of dominant follicles on the day of HCG administration. Timepoint: Day of occurrence of at least one ovarian follicule =16 mm in diameter. Method of measurement: Number of dominant follicles.