The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties
- Conditions
- Wrinkle
- Interventions
- Other: Cleansing BalmOther: Toning EssenceOther: Facial SerumOther: MoisturizerOther: Eye Cream
- Registration Number
- NCT05688527
- Lead Sponsor
- Integrative Skin Science and Research
- Brief Summary
This study is to analyze the effects of a 5-step skin care regimen on various skin parameters such as pigmentation, and firmness and elasticity of the skin around the eyes. The 5 facial products in the regimen are a cleansing balm, a toner, a serum, a moisturizer. and an eye cream.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 36
- Men and women between the ages of 35 years old and 65 years old.
- Must have fine lines and wrinkles around the eyes.
- Individuals who are pregnant or breastfeeding.
- Prisoners
- Adults unable to consent
- Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study.
- Subjects using any topical retinoid, hydroquinone, kojic acid, bakuchiol, hyaluronic acid or benzoyl peroxide containing topical product within 2 weeks of starting study or any subject unwilling to refrain from washout prior to enrollment.
- Subjects with any facial treatments in the past 6 months and who are unwilling to withhold facial cosmetic treatments during the study including botulinum toxin, injectable fillers, microdermabrasion, intense pulsed light (IPL), peels, laser treatments, acid treatments, tightening treatments, facial plastic surgery, or any other medical treatment administered by a physician or skin care professional which is designed to improve the appearance of facial skin.
- Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 5 Step Skin Care Regimen Toning Essence The subject uses 5 facial products in the regimen; a cleansing balm, a toner, a serum, a moisturizer and an eye cream. 5 Step Skin Care Regimen Cleansing Balm The subject uses 5 facial products in the regimen; a cleansing balm, a toner, a serum, a moisturizer and an eye cream. 5 Step Skin Care Regimen Facial Serum The subject uses 5 facial products in the regimen; a cleansing balm, a toner, a serum, a moisturizer and an eye cream. 5 Step Skin Care Regimen Moisturizer The subject uses 5 facial products in the regimen; a cleansing balm, a toner, a serum, a moisturizer and an eye cream. 5 Step Skin Care Regimen Eye Cream The subject uses 5 facial products in the regimen; a cleansing balm, a toner, a serum, a moisturizer and an eye cream.
- Primary Outcome Measures
Name Time Method Appearance of facial wrinkles 8 weeks Change in wrinkle severity measured by photographic analysis (BTBP 3D Camera System)
Change in skin pigmentation in the undereye area 8 weeks Change in skin pigmentation in the undereye area by Skin colorimetric analysis of pigment
- Secondary Outcome Measures
Name Time Method Transepidermal water loss 8 weeks Change in transepidermal water loss measurement with Vapometer
Skin volume 8 weeks Change in skin volume/plumpness by photographic image analysis with BTBP 3D Camera System
Self-perception of skin parameters 8 weeks Survey based self-assessment of facial fine lines and wrinkles, skin smoothness, skin firmness
Appearance of facial wrinkles Change in wrinkle severity measured by photographic analysis (BTBP 3D Camera System) 4 weeks
Skin texture/roughness 8 weeks Change in the appearance of photographic analysis of texture/roughness with BTBP 3D Camera System
Tolerability of products 8 weeks Questionnaire based self-assessment about the tolerability of the topical skin products
Skin hydration 8 weeks Change in skin hydration by SkinMoistureMeterSC measurement
Trial Locations
- Locations (1)
Integrative Skin Science and Research
🇺🇸Sacramento, California, United States