Monocentric Study on the Use of Teriparatide in Children With hypoparathyroïdism
- Conditions
- Hypoparathyroidism
- Interventions
- Other: Serum calcium concentrations results
- Registration Number
- NCT04126941
- Lead Sponsor
- Hospices Civils de Lyon
- Brief Summary
Pediatric hypoparathyroidism is an orphan disease. Conventional management combines native and active vitamin D, calcium supplementation and sometimes phosphate binders, with the risk of long term hypercalciuria, nephrocalcinosis and further renal impairment. The use of teriparatide has been reported in adults (daily or bi-daily subcutaneous infusions) and in children (rather continuous subcutaneous infusion) as second-line therapy.
The objective of this study is to obtain efficacy and safety data on the use of teriparatide in children with hypoparathyroidism to improve our knowledge of their management.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 9
Inclusion Criteria
- Patients with hypoparathyroidism
- Patients treated with teriparatide
- Patients followed in the reference center for calcium and phosphate metabolism diseases of Lyon.
- For children under 18: patient and parent (s) / parent having been informed of the study and having expressed their non-opposition
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Exclusion Criteria
- No social security support
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Teriparatide Serum calcium concentrations results Patients with hypoparathyroidism treated by teriparatide
- Primary Outcome Measures
Name Time Method Serum calcium concentration 3 months after treatment initiation
- Secondary Outcome Measures
Name Time Method Serum calcium concentration 3 years after treatment initiation
Trial Locations
- Locations (1)
Service de Néphrologie, Rhumatologie et Dermatologie Pédiatriques - Hôpital Femme Mère Enfant
🇫🇷Bron, France