Oral Mucosal Graft Versus Labial Graft in Female Urethroplasty: A Prospective Comparative Study
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Tanta University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Urine flow rate
Study Overview
Brief Summary
This study aims to compare the oral versus labial graft in female urethroplasty in female urethral stricture.
Detailed Description
Female urethral stricture is an uncommon condition with an estimated prevalence of 4%-13% in women with bladder outlet obstruction.
Urethral reconstruction may become the treatment of choice in stricture recurrence following the failure of minimally invasive procedures. and the use of flaps and grafts has all been proposed. Different materials (e.g., vaginal and genital mucosal graft or flap, bladder mucosal flap, and oral mucosal graft) have been reported for augmentation urethroplasty.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Female patients with urethral stricture.
- •Female patients with non-traumatic urethral stricture.
Exclusion Criteria
- •Female patients with traumatic urethral stricture.
- •Female patients with systemic contraindications of surgery like bleeding disorders.
Arms & Interventions
Group 1
Patients will be admitted for the surgical management by the oral mucosal graft urethroplasty with the anterior onlay technique.
Intervention: Oral mucosal graft (Procedure)
Group 2
Patients will be admitted for the surgical management by the labial graft urethroplasty with the anterior onlay technique.
Intervention: Labial graft (Procedure)
Outcomes
Primary Outcomes
Urine flow rate
Time Frame: 6 months post-procedure
Urine flow rate will be recorded.
Secondary Outcomes
No secondary outcomes reported
Investigators
Mohamed Ibrahim Ahmed Elmaadawy
Lecturer of Urology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Tanta University