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A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia

Phase 3
Completed
Conditions
10003816
Warm antibody autoimmune hemolytic anemia
10018849
Registration Number
NL-OMON55183
Lead Sponsor
Rigel Pharmaceuticals, Inc.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
2
Inclusion Criteria

1. Subject must be willing and able to give written informed consent by signing
an IRB approved Informed Consent Form prior to undergoing any study-specific
procedures.
2. Subject must have completed all 24 weeks of participation in the study
C-935788-057.
3. Female subjects must be either post-menopausal for at least 1 year or
surgically sterile; or, if of childbearing potential, must not be pregnant or
lactating and must agree to use a highly effective method of birth control
throughout the duration of the trial and for 30 days following the last dose.
Acceptable methods of birth control are defined as: hormonal contraception
(pill, injection or implant) used consistently for at least 30 days prior to
baseline an intrauterine device (IUD), or intrauterine hormone-releasing system
(IUS), or true abstinence (i.e. abstinence is in line with the preferred and
usual lifestyle of the subject).
4. In the investigator*s opinion, the subject has the ability to understand the
nature of the study and any hazards of participation and to communicate
satisfactorily with the investigator.

Exclusion Criteria

1. Any subject who discontinued participation in Study C-935788-057 prior to
Week 24.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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