Retrospective Longitudinal Study of Gestational Weight Gain Among Chinese Pregnant Women
- Conditions
- Gestational Weight Gain
- Registration Number
- NCT03154268
- Lead Sponsor
- West China Hospital
- Brief Summary
The purpose of this study is to investigate the reference ranges and rates of gestational weight gain among Chinese pregnant women, and to analyze the correlation between gestational weight gain and adverse outcomes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 10422
- Deliveries between January 2013 and December 2014;
- Gestational age between 37 weeks or older and less than 42 weeks;
- Registration with care documents at the first prenatal visit prior to the 15th gestational week;
- Had at least five follow-up visits until delivery.
None
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ICP After 14th gestational weeks till delivery, about 6 months Intrahepatic cholestasis of pregnancy.
Neonatal defect Within 1 month after delivery Neonatal defect.
Gestational diabetes After 24th gestational weeks, about 4 months By oral glucose tolerance test between 24th and 28th gestational weeks (fasting glucose ≥5.1 mmol/L, 1-h glucose ≥10.0 mmol/L, 2-h glucose ≥8.5 mmol/L; one abnormal result sufficient).
Hematological diseases During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year Iron-deficiency anemia, thalassemia, hemophilia, idiopathic thrombocytopenic purpura, aplastic anemia, or disseminated intravascular coagulation.
Placenta previa During pregnancy till delivery Placenta partially or entirely covered the lower uterine segment diagnosed using antenatal ultrasound.
Thyroid disease During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year Hyperthyroidism or hypothyroidism.
ICU admission During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year Admission to intensive care unit.
Macrosomia within 1 month after delivery Birth weight \>4000 g.
Infant of low-birth weight within 1 month after delivery Birth weight \<2500 g.
Preeclampsia After 20th gestational weeks till delivery, about 5 months Maternal systolic pressure ≥140 mmHg and/or diastolic pressure ≥90 mmHg during gestation. Urine protein ≥5.0 g within 24h, urine volume \<400 mL. HELLP syndrome or pulmonary edema present.
Eclampsia After 20th gestational weeks till delivery, about 5 months Tonic-clonic seizures (convulsions) in preeclampsia patients, including convulsions and coma, not due to pre-existing or organic brain disorders.
Ruptured uterus During delivery Rupture of maternal uterus confirmed by laparotomy.
Placental abruption After 20th gestational weeks till delivery, about 5 months Abruption of a normally positioned placenta before delivery, diagnosed by clinical symptoms, ultrasound, fetal heart monitoring, or laboratory tests.
Postpartum hemorrhage Within 24h after delivery Postpartum bleeding volume ≥500 mL.
Hepatic diseases During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year Hepatitis-B/C/E virus infection, acute fatty liver disease, or severe hepatitis.
Gynecological diseases During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year Uterine fibroids, ovarian cyst, cervical carcinoma, pelvic inflammation, or ovarian carcinoma.
Respiratory diseases During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year Pneumonia, bronchitis, asthma or pulmonary tuberculosis.
Maternal death During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year Maternal death.
Neonatal ICU admission Within 1 month after delivery Admission to neonatal intensive care unit.
Neonatal death Within 1 month after delivery Neonatal death.
Large for gestational age Within 1 month after delivery Neonatal weight, length, or head circumference above the 90th percentile for that gestational age.
Small for gestational age Within 1 month after delivery Neonatal weight, length, or head circumference below the 10th percentile for that gestational age.
Neonatal adverse outcomes Within 1 month after delivery There occurred one or more of macrosomia, low-birth weight, neonatal ICU admission, neonatal death, large for gestational age, small for gestational age, or neonatal defect.
Maternal adverse outcomes During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year There occurred one or more of preeclampsia, eclampsia, ICP, placenta previa, gestational diabetes, ruptured uterus, placental abruption, postpartum hemorrhage, hepatic diseases, hematological diseases, gynecological diseases, respiratory diseases, thyroid disease, ICU admission, or maternal death.
- Secondary Outcome Measures
Name Time Method