Impact of IPT With Sulfadoxin Pyrimetamin on Pregnant Women and Their Babies Outcomes in Peri-urban Areas of Bobo-Dioulasso(Burkina Faso)

Completed

• Conditions: Malaria, Pregnancy

• Registration Number: NCT01255605
• Lead Sponsor: Université Polytechnique de Bobo-Dioulasso

Brief Summary

The purpose of this is to determine the impact of intermittent preventive treatment (IPT) with sulfadoxine-pyrimethamine (SP) on the morbidities associated with malaria in pregnant women and newborns in rural peri-urban areas of Bobo-Dioulasso, 5 years after its implemented.

Detailed Description

Malaria in pregnant women is a crucial issue in Burkina Faso. Faced with this problem, a strategy based on the use of treated nets and intermittent preventive treatment (IPT) based on sulfadoxine-pyrimethamine (SP) was adopted in 2005. Five years after its implementation, the investigators will check whether this strategy is still effective in the preventing maternal and congenital malaria on the one hand and maternal anemia, low birth weight and prematurity on the other hand.

Study Timeline

• Study Start: 2010-09
• Study First Submitted: 2010-12-06
• Study First Submitted QC: 2010-12-06
• Study First Posted: 2010-12-07
• Study Completion: 2011-06
• Status Verified: 2012-06
• Last Update Submitted: 2012-06-15
• Last Update Posted: 2012-06-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 772

Inclusion Criteria

• Residing in the health area of Lafiabougou or secteur 24
• Having agreed to give free and informed consent

Exclusion Criteria

• Bleeding from during the pregnancy
• eclampsia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Peripheral and placental malaria	Peripheral malaria : at antenatal clinics and at delivery. Placental malaria: at delivery	The investigators will check if pregnant women have any malaria parasites by making a finger prick thick respectively at antenatal clinics and at delivery. A placental thin smear will be made at delivery.

Secondary Outcome Measures

Name	Time	Method
Maternal anemia, congenital malaria,low birth weight, prematurity.	Maternal anemia: at antenatal clinics and at delivery. Congenital malaria: at delivery. Low birth weight: at delivery. Prematurity: at delivery.	The investigators will check pregnant women haemoglobin level.A level\< 11g/dl will be considered as anemia.; Congenital malaria will be assessed through cord blood smear. Birth weight \<2500g will be considered as low birth weight. Prematurity designs any birth before 37 gestation weeks.

Trial Locations

Locations (1)

Institut Supérieur des Sciences de la Santé/Université Polytechnique de Bobo-Dioulasso; 🇧🇫 Bobo-Dioulasso, Houet, Burkina Faso