Evaluation of Betaxolol in improving the acute phase of patients with mild to moderate Traumatic Brain Injury
Phase 3
Recruiting
- Conditions
- Traumatic Brain Injury.Intracranial injury
- Registration Number
- IRCT20240415061488N1
- Lead Sponsor
- Bagheiat-allah University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 104
Inclusion Criteria
Patients with mild to moderate traumatic brain injury (GCS score of 9 or above)
Age 18 to 65 years old
Exclusion Criteria
Patients with penetrating head trauma
Unspecified time of trauma
Patients with spinal cord injury
Patients with cardiovascular diseases
Hemodynamic instability
Candidates for craniotomy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Score of Glasgow Outcome Scale Extended (GOSE). Timepoint: Day 1 and 14 after taking medication. Method of measurement: Glasgow Outcome Scale Extended (GOSE) Questionnaire.
- Secondary Outcome Measures
Name Time Method Score of The Working Memory Questionnaire. Timepoint: Day 1 and 14 after taking medication. Method of measurement: The Working Memory Questionnaire.;Score of Visual analogue scale (VAS). Timepoint: Day 1 and 14 after taking medication. Method of measurement: Visual analogue scale (VAS).;Score of Mini Mental State Examination (MMSE). Timepoint: Day 1 and 14 after taking medication. Method of measurement: Score of Mini Mental State Examination (MMSE).;Presence of drug side effects. Timepoint: Day 1 and 14 after taking medication. Method of measurement: If the patient confirms any side effects of the drug Yes otherwise No.