Endoplasmic Reticulum Stress and Endometriosis Releated Pain
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Endometriosis
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
- Enrollment
- 86
- Locations
- 1
- Primary Endpoint
- Evaluation of the correlations between the results of XBP-1 levels and the stages and pain symptoms of endometriosis.
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The correlation between painful symptoms (dysmenorrhea, dysparonia, dysuria, chronic pelvic pain) symptoms and endoplasmic reticulum stress was investigated in 86 patients diagnosed with endometriosis. For this, xbp-1 (x box binding protein-1) level was measured in patients. XBP-1 is an endoplasmic reticulum stress indicator and is known to be involved in pain pathogenesis.
Detailed Description
Women between the ages of 18-50 who were diagnosed with endometriosis by surgery and ultrasound, without known rheumatological or metabolic diseases were included in the study. Most of the patients are composed of newly diagnosed patients.
Investigators
Pınar Yalcin bahat
Principal Investigator
Kanuni Sultan Suleyman Training and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •diagnosed endometriosis with ultrasound or surgery
- •no metabolic diseases
- •no rheumatological diseases
Exclusion Criteria
- •Immune modulator, hormonal, anti-inflammatory use history in the last 3 months
Outcomes
Primary Outcomes
Evaluation of the correlations between the results of XBP-1 levels and the stages and pain symptoms of endometriosis.
Time Frame: 5 months
Secondary Outcomes
- serum XBP-1levels in patients wit endometriosis(5 months)