Cancer rehabilitation for Hepato-Pancreato-Biliary cancer patients undergoing surgical treatment - CREST study

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 154 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

暂无简介。

•* Undergoing curative intent surgery for HPB malignancies. Liver surgery will be defined as major if a left or right (extended) hemihepatectomy or if 3 or more segments are resected and minor if less than 3 segments are resected.
•* Clinically suspect or histologically confirmed liver, bile duct, pancreatic carcinoma or invasive IPMN;
•* Life expectancy of at least six (6) months;
•* Resection performed
•* Fatigue score * 4 on a numeric rating scale (NRS) with scores of 0 to 10
•* Able to read and understand the Dutch language;
•* Written informed consent.

•- Bone metastases or other high risk of fracture;
•- Not able to perform basic activities of daily living (ECOG *3);
•- Decompensated heart disease, uncontrolled hypertension (systolic blood pressure > 200 mmHg or diastolic blood pressure > 110 mmHg), heart failure (NYHA Class II or greater) or chronic obstructive pulmonary disease causing fatigue;
•- Living in nursing homes;
•- Cognitive impairment;
•- BMI <15 kg2/m2, >5% weight loss per month or other health problems that would not allow physical exercise training;
•- Anxiety or depression requiring psychiatric consultation;
•- Cancer treatment in the previous 3 years (except basal skin cancer);
•- Participation in other studies containing elements of physical exercise or psychological therapy.

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