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Platelet rich fibrin effects on third molar surgery

Completed
Conditions
Bilateral impacted third molars
Oral Health
Registration Number
ISRCTN16849867
Lead Sponsor
Ankara University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
30
Inclusion Criteria

1. Healthy patients without significant medical diseases or a history of bleeding problems
2. Symmetrical impacted third molars which feature the same level of surgical difficulty that require the same surgical technique to be performed
3. The third molars in the Class I, Level B position (according to Pell &Gregory) and in the vertical positions according to Winter
4. Aged 17–27 years

Exclusion Criteria

1. Pregnant and lactating women
2. Signs of pericoronitis
3. Chronic use of medications such as antihistamines, non-steroidal anti-inflammatory drugs (NSAID), steroids and antidepressants which would complicate the evaluation of their postoperative response

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pain is measured using a visual analogue scale (VAS) and Verbal rate scale (VRS) at 6 and 12 hours and 1, 2, 3 and 7 days after surgery.
Secondary Outcome Measures
NameTimeMethod
Edema is measured using a flexible ruler at baseline, 2 and 7 days.
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