跳至主要内容
临床试验/NCT04265157
NCT04265157Unknown不适用

Hepato-duodenal Ligament Occlusion Versus Classic Technique During Recipient Hepatectomy in Liver Transplantation

Assiut University0 个研究点目标入组 50 人开始时间: 2020年3月最近更新:
适应症

试验速览

阶段
不适用
入组人数
50
主要终点
The amount of intraoperative blood loss measure by Cubic Cm

研究概览

简要总结

Liver transplantation was historically associated with massive blood loss. Many factors have contributed to the decline in bleeding and transfusion in the past two decades including refinement of surgical techniques, anesthetics management and the use of point of care guided goal-directed hemostatic therapies. Increasing awareness of the adverse associations of allogenic transfusion has driven the quest for transfusion-free transplantation. Pre-operative management of preoperative anemia and targeted correction of coagulopathy is done to decrease blood transfusion. Liver transplantation is associated with the potential for massive operative blood loss, which has been recognized as one of the main causes of morbidity and mortality after liver transplantation. Therefore, a fine surgical procedure to reduce intraoperative hemorrhage is necessary for favorable outcomes of liver transplantation.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients undergoing Living Donor Liver Transplantation accepted according to hospital protocol
  • All patients with liver Cirrhosis who have Porto systemic collaterals based on ct angiography

排除标准

  • Acute fulminant liver failure

结局指标

主要结局

The amount of intraoperative blood loss measure by Cubic Cm

时间窗: 2 hours

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmed mahmoud mohammed elkoussy

Assisstant lecturer

Assiut University

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