Incidence, Duration, and Clinical Impact of Recovery-Period Hypoxemia Following Sedated Upper Gastrointestinal Endoscopy: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Recovery-Period Respiratory Events
研究概览
简要总结
Sedation during upper gastrointestinal endoscopy may lead to respiratory events not only during the procedure but also in the early recovery period. Although most hypoxemic episodes are considered transient, their frequency, duration, and clinical consequences during recovery remain insufficiently defined.
This prospective observational study aims to evaluate the incidence, duration, and clinical impact of recovery-period hypoxemia following sedated upper gastrointestinal endoscopy. Hypoxemia is defined as SpO₂ <90% lasting ≥10 seconds. Associated respiratory events and potential risk factors will be analyzed without altering routine clinical practice.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged ≥18 years
- •Scheduled for upper gastrointestinal endoscopy (EGD) under anesthesiologist-administered sedation
- •Able to undergo post-procedure monitoring in the recovery unit
- •Provided written informed consent for participation and data use
排除标准
- •Colonoscopy or combined procedures (EGD + colonoscopy)
- •Emergency procedures or procedures performed under intensive care conditions
- •Requirement for endotracheal intubation, noninvasive ventilation, or advanced airway support during the procedure
- •Known severe upper airway anatomical abnormalities, facial deformity, or tracheostomy
- •Inability or refusal to provide informed consent
- •Incomplete or unavailable recovery-period oxygen saturation monitoring data
结局指标
主要结局
Recovery-Period Respiratory Events
时间窗: From end of procedure (scope-out) until discharge from recovery unit
Occurrence of respiratory events during the recovery period following sedated upper gastrointestinal endoscopy, defined as at least one of the following: SpO₂ \<90% lasting ≥10 seconds Requirement for airway maneuver (jaw-thrust, chin-lift, OPA/NPA, mask ventilation) Escalation or re-initiation of supplemental oxygen
次要结局
未报告次要终点
研究者
İlke Dolgun
Assoc. prof
Istinye University