The effect of black cumin on non alcholic fatty liver
Phase 2
- Conditions
- on alcholic fatty liver.Fatty (change of) liver, not elsewhere classified
- Registration Number
- IRCT2017012232109N1
- Lead Sponsor
- Vice Chancellor for research of Ahvaz Jundishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
patients aged 20 to 60 years diagnosed with nonalcoholic fatty liver by ultrasound, confirmed by a radiologist and a gastroenterologist.
Exclusion criteria: pregnancy and lactation; liver transplantation; smoking; alcohol and drug abuse; consuming drugs such as corticosteroids, amiodarone, tamoxifen, methotrexate; receiving total parenteral nutrition; rapid weight loss; diabetes; heart failure; thyroid problems; kidney disease; hereditary hemochromatosis and Wilson disease; have a positive test for hepatitis C, B and autoimmune hepatitis; alpha-1 antitrypsin deficiency.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tumor necrosis factor. Timepoint: before and 8 weeks after intervention. Method of measurement: ELISA.;Interleukin 6. Timepoint: before and 8 weeks after intervention. Method of measurement: ELISA.;Liver enzymes(aspartate aminotransfrase,alanin aminotransferase,gama glutamil transferase). Timepoint: before and 8 weeks after intervention. Method of measurement: Labratory kits.;C reactive protein. Timepoint: before and 8 weeks after intervention. Method of measurement: ELISA.;Lipid profiles(triglycrid,HDL,LDL and total chollestrol). Timepoint: before and 8 weeks after intervention. Method of measurement: Labratory kits.;Insulin. Timepoint: before and 8 weeks after intervention. Method of measurement: ELISA.;Fast blood sugar. Timepoint: before and 8 weeks after intervention. Method of measurement: Enzymatic chlorometric method.
- Secondary Outcome Measures
Name Time Method Waist to hip ratio. Timepoint: before and 8 weeks after intervention. Method of measurement: Inelastic tape without putting pressure on the body.;Body mass index. Timepoint: before and 8 weeks after intervention. Method of measurement: The ratio of weight in kilograms by the square of height in meters.;Systolic and diastolic blood pressure. Timepoint: before and 8 weeks after intervention. Method of measurement: Sphygmomanometer.