Neural Therapy in Cesareans

Not yet recruiting

• Conditions: Visual Analogue Scale
• Interventions: Drug: neural therapy

• Registration Number: NCT06999200
• Lead Sponsor: Haseki Training and Research Hospital

Brief Summary

In the management of pain after Caesarean section (C/S), opioid or nonsteroidal anti-inflammatory parenteral drugs are applied. These drugs are insufficient in some cases and may cause pain attacks during the day. Higher doses and repeated drug applications or combined drug administration may cause drug side effects and interactions. Alternative applications to provide analgesia include subcutaneous and intracutaneous local anesthetic application to the wound site. Although the effectiveness of these applications has been tested in individuals with different clinical characteristics and has been shown to be largely more successful, they have not been sufficiently introduced into routine practice. There is a need to review the pain methods suggested in the literature and develop new solutions that can be applied more optimally, improve the patient's pain management in the postoperative period, and increase their quality of life and satisfaction.

It aims to evaluate the success of subcutaneous and intracutaneous local anesthesia applications compared to traditional applications, and to find the most optimal management.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-05
• Study First Submitted: 2025-05-07
• Study First Submitted QC: 2025-05-22
• Last Update Submitted: 2025-05-22
• Study First Posted: 2025-05-31
• Last Update Posted: 2025-05-31
• Study Start: 2025-06-10
• Primary Completion: 2025-09-10
• Study Completion: 2025-10-10

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 156

Inclusion Criteria

• Healthy pregnancy,
• Term (>37 weeks) and preterm (28-34 weeks) pregnancy,
• Cases that received general anesthesia for cesarean section,
• Cases with and without labor,
• Cases with and without obesity,
• Cases that had their first or second cesarean section

Exclusion Criteria

• Pregnant women under 19 years of age,
• Those with a history of allergic reactions to analgesics to be used,
• Stillbirth,
• Surgical complications during C/S and placement of an abdominal drain,
• No head or breech presentation during C/S,
• Occiput posterior presentation during C/S,
• Anhydramnios and polyhydramnios,
• Allergic reactions to the drugs used in the study, alcohol dependence, drug and substance dependence, chronic pain syndrome, neuropathic pain disorder history,
• History of clinically significant cardiovascular, pulmonary, hepatic, renal, neurological, psychiatric, metabolic disease.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Subcutaneous local anesthesia group	neural therapy	who received subcutaneous local anesthesia at the end of C/S surgery
Intracutaneous local anesthesia group	neural therapy	who received intracutaneous local anesthesia at the end of C/S surgery
Parenteral analgesia group	neural therapy	who received parenteral analgesia after C/S surgery

Primary Outcome Measures

Name	Time	Method
Visual analogue scale	48 hours	1=no pain, 10=worst pain