Effects of Watermelon or Low-fat Cookie Consumption on Wellness

Not Applicable

Recruiting

• Conditions: Overweight and Obesity
• Interventions: Other: Low-fat cookies; Other: Watermelon

• Registration Number: NCT06323070
• Lead Sponsor: San Diego State University

Brief Summary

The objective of the proposed research is to determine the effects of fresh watermelon consumption on physiological indicators of wellness regarding sexual, skin and gut health in adults.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-03-01
• Study First Submitted: 2024-03-14
• Study First Submitted QC: 2024-03-14
• Study First Posted: 2024-03-21
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-26
• Last Update Posted: 2025-04-01
• Primary Completion: 2025-12
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Generally healthy subjects
• BMI 20-40 kg/m2

Exclusion Criteria

• Smoker
• Pregnant woman
• Required antibiotics use
• Required dietary supplement use
• Required medication of metabolic disorders, mental health and sexual health
• Allergy to watermelon or wheat

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Low-fat cookies	Low-fat cookies	Subjects consume 100 kcal of low-fat cookies daily for 4 weeks.
Watermelon	Watermelon	Subjects consume 100 kcal of watermelon daily for 4 weeks.

Primary Outcome Measures

Name	Time	Method
Change of sexual health questionnaire scores	Baseline and week 4	Change of sexual health questionnaire scores will be determined to examine effects of watermelon consumption vs low-fat cookies.
Change of skin hydration scores	Baseline, 1 min post application and week 4 consumption	Change of skin hydration scores will be determined to examine effects of watermelon consumption vs low-fat cookies.
Change of microbiome diversity	Baseline and week 4	Change of skin hydration scores will be determined to examine effects of watermelon consumption vs low-fat cookies.

Secondary Outcome Measures

Name	Time	Method
Change of depression questionnaire scores	Baseline and week 4	Change of depression questionnaire scores will be determined to examine effects of watermelon consumption vs low-fat cookies.

Trial Locations

Locations (1)

School of Exercise and Nutritional Sciences; 🇺🇸 San Diego, California, United States