Consequence of Injectable Platelets Rich Fibrin Versus Microosteopeforationon Root Resorption During Orthodontic Intrusion of Incisor Teeth: A Comparative Clinical Study
试验速览
- 阶段
- 1 期
- 状态
- Enrolling By Invitation
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- to compare the effect of injectable platelets rich fibrin and micro-osteoperforations on root resorption during orthodontic intrusion of incisors.
研究概览
简要总结
Consequence of injectable platelets rich fibrin versus microosteopeforation on root resorption during orthodontic intrusion of incisor teeth
详细描述
Consequence of injectable platelets rich fibrin versus microosteopeforation on root resorption during orthodontic intrusion of incisor teeth: A comparative clinical study
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 22 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with age range between 12-16 years.
- •Overbite > 40% indicated for maxillary intrusion.
- •Mild to moderate crowding of upper incisors.
- •All permanent teeth erupted (excluding 3rd molars).
- •No previous orthodontic treatment.
- •Good oral hygiene with no previous periodontal surgery.
排除标准
- •Transverse and/or vertical skeletal dysplasia or craniofacial malformation.
- •Retained primary or missing permanent teeth in the maxillary anterior area, and any kind of tooth/root shape anomaly.
- •Patients with root resorption, impacted canines, or dental anomalies.
- •Poor oral hygiene
- •Present or history of periodontal diseases.
- •Systemic diseases or regular use of medications that could interfere with orthodontic tooth movement.
- •History of trauma affecting the maxillary incisors.
- •Endodontically treated upper anterior teeth.
研究组 & 干预措施
Group I
who will receive intrusive arches after leveling and alignment assisted with i-PRF according to standardized protocol
干预措施: injectable platelet rich fibrin and microosteoperforation (Combination Product)
Group II
Will includes 9 patients who will receive intrusive utility arches after leveling and alignment assisted with (MOPs) according to standardized protocol.
干预措施: injectable platelet rich fibrin and microosteoperforation (Combination Product)
结局指标
主要结局
to compare the effect of injectable platelets rich fibrin and micro-osteoperforations on root resorption during orthodontic intrusion of incisors.
时间窗: post interventionalal at 6months
amount of root resorption
次要结局
未报告次要终点
研究者
farouk ahmed hussein
Principal Investigator
Al-Azhar University