The Development of a Screening Questionnaire to Discriminate Autism Spectrum Disorder and Schizotypal Disorder, and Validation of the Danish Version of RAADS-R
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 600
- 试验地点
- 2
- 主要终点
- ZAQ
研究概览
简要总结
The aim of the study is to investigate the validity, reliability and clinical features of a Danish version of the Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R). A self-reporting scale devise used as a supplementary questionnaire in diagnosing autism spectrum disorder (ASD) in adults. Furthermore the validity of novel screening questionnaire: SchiZotypal Autism Questionnaire (ZAQ), will be investigated. ZAQ is developed to discriminate Schizotypal Disorder from ASD.
详细描述
The study has 2 parts.
Part 1:
The objective is to develop and validate a self-report screening questionnaire to efficiently discriminate between Schizotypal Disorder (SD) and Autism Spectrum Disorder (ASD) within the adult population. Discriminating ASD from SD in a clinical setting is a complex and time-consuming task, as they share considerable features both at the symptomatic and the diagnostic criteria. A pilot version of this questionnaire have been developed with 139 questions and named schiZotypy Autism Questionnaire (ZAQ), to discriminate between these conditions.
Part 2:
RAADS-R scale, which is a clinical tool that aims to better identify autism spectrum disorders The scale is a self-administered questionnaire completed by the patient himself assisted by a clinician (psychiatrist, psychologist) which ensures the understanding of issues and the choice of answers. The scale contains 80 items including 64 questions describe specific symptoms of autism spectrum disorders and 16 questions to describe non-symptomatic behaviors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Al patient referred to the outpatient clinic for ADHD and Autism at PCG, in the research period, for diagnostic assessment of Autism Spectrum Disorder (Pervasive Developmental Disorder, infantile autism, atypical autism and Asperger Syndrome)
- •WAIS > 85, or Raven or no-clinical suspicion and education level of 11 years or above
- •Completion of
- •Clinical assessment
- •Adult Asperger Assessment (AAA)
- •Psychopathology evaluation using DSM-V
- •A conclusion based on interdisciplinary consensus
排除标准
- •Insufficient Danish language skills
- •Acute psychiatric illness prompting departure/dismissal from the diagnostic assessment
结局指标
主要结局
ZAQ
时间窗: up to 1 month
schiZotypy Autism Questionnaire
RAADS-R-DK
时间窗: Up to 1 month
Ritvo Autism Asperger Diagnostic Scale-Revised-Danish version
次要结局
- AQ(Up to 1 month)
- WHO-DAS 2.0(Up to 1 month)
- WHO-5(Up to 1 month)
研究者
Rizwan Parvaiz
Medical doctor, Director of Autism Research
Glostrup University Hospital, Copenhagen