IRCT20190917044805N2CompletedPhase 2
Effects of High-dose Vitamin C on Treatment, Clinical Symptoms and Laboratory Signs of Iranian COVID-19 Patients: A Double Blind Randomized Clinical Trial
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Enrollment
- 60
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to no limit (—)
- Sex
- All
Inclusion Criteria
- •Older than 18 years old
- •admission with moderate to severe COVID-19 based on WHO definition
- •Illness of any duration, and at least one of the following: Radiographic infiltrates by imaging (chest x-ray, CT scan, etc.), or Clinical assessment AND respiratory rate > 30 breaths/min; or severe respiratory distress; or SpO2 < 90% on room air.
- •Willing and be able to provide written informed consent prior to performing study procedures
Exclusion Criteria
- •Participation in any other clinical trial of an experimental treatment for COVID-19
- •Critical ill patients that need invasive mechanical ventilation
- •Stage 4 severe chronic kidney disease or requiring dialysis (i.e. eGFR < 30)
- •Patients with past medical history of kidney stone
- •Pregnancy or breastfeeding
- •Documented diagnosis of cancer?
- •History of G6PD deficiency ?and interstitial lung disease ?
- •More than 1 gram/day intake of vitamin C ?supplement in last 7 days
Investigators
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