Carotid Artery Corrected Flow Time and Fluid Responsiveness in Geriatric Patients

Completed

• Conditions: Fluid Responsiveness; Common Carotid Artery

• Registration Number: NCT06087250
• Lead Sponsor: Marmara University

Brief Summary

Carotid blood flow and corrected carotid flow time (Carotid Flow Time (FTc)) provide information about left ventricular preload and inversely correlate with systemic vascular resistance. The reliability in assessing fluid responsiveness has been demonstrated in studies involving invasive cardiac output measurements. In the elderly patient population where arterial elasticity can be compromised, there is no existing data in literature that determines the reliability and predictive value of FTc after general anesthesia induction.

Detailed Description

Doppler ultrasound of the common carotid artery has begun to be used as a potential non-invasive tool for assessing hemodynamic status. Its non-invasive nature, ability to be applied independently of the patient's position, ease of application due to the superficial location of the carotid artery, and resistance to intrathoracic pressure changes are among its advantages. Carotid blood flow and corrected carotid flow time (Carotid Flow Time (FTc)) provide information about left ventricular preload and inversely correlate with systemic vascular resistance. Additionally, the velocity time integral (VTI) measuring blood flow through the carotid artery during systole, when multiplied by the cross-sectional area of the carotid artery, allows for the determination of flow within the carotid artery. The reliability in assessing fluid responsiveness has been demonstrated in studies involving invasive cardiac output measurements. In the elderly patient population where arterial elasticity can be compromised, there is no existing data in literature that determines the reliability and predictive value of FTc after general anesthesia induction.

Study Timeline

• Study Start: 2023-08-01
• Study First Submitted: 2023-10-12
• Study First Submitted QC: 2023-10-12
• Study First Posted: 2023-10-17
• Primary Completion: 2023-10-24
• Study Completion: 2023-10-24
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-01
• Last Update Posted: 2024-04-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• geriatric patient (older than 65 years of age) having surgery under general anesthesia

Exclusion Criteria

• Common carotid artery stenosis, common carotid artery disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
carotid corrected flow time (cFT)	1 hour	the ability ofc FT to predict fluid responsiveness

Secondary Outcome Measures

Name	Time	Method
cutt-of value of cFT	1 hour	the cutt-of value of cFT to predict fluid responsiveness

Trial Locations

Locations (1)

Marmara University Hospital; 🇹🇷 Istanbul, Turkey