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Clinical Trials/NCT04559659
NCT04559659
Unknown
N/A

Study of the Relationship Between Respiratory Muscle Strenght, Peripheral Muscle Blood Flow and Gait Speed in the Elderly

Hospital Israelita Albert Einstein1 site in 1 country50 target enrollmentAugust 20, 2019
ConditionsAge Problem

Overview

Phase
N/A
Intervention
Not specified
Conditions
Age Problem
Sponsor
Hospital Israelita Albert Einstein
Enrollment
50
Locations
1
Primary Endpoint
Peripheral muscle blood flow, gait speed and handgrip strength
Last Updated
4 years ago

Overview

Brief Summary

The pourpose of this study is to verify if have relationship between respiratory muscle strenght, peripheral muscle blood flow and gait speed in the elderly.

Detailed Description

The hypothesis of this study is that elderly with inspiratory muscle weakness will present lower peripheral blood flow and consequently lower walking speed. The main aim of the study is to verify if the peripheral muscular blood flow in the elderly is different between patients with and without decrease in inspiratory muscle strength. As secondary objectives, it will be evaluated the correlation between inspiratory muscle strength and gait speed and quality of life, as well as gait speed and peripheral muscle blood flow. Fifty elderly patients of both sexes, over 65 years, from Vila Mariana Einstein Outpatient Clinic and Cora Residencial Senior, will be included to evaluate Maximum Inspiratory Pressure (Pimáx), Maximum Expiratory Pressure (Pemáx), Spirometry (FVC, PF, FEV1), 4.6m Walk Test, Quality of life for the elderly (WHOQOL old), Mini Mental Test, Body Mass Index (BMI) and peripheral muscle blood flow by venous occlusion plethysmography.

Registry
clinicaltrials.gov
Start Date
August 20, 2019
End Date
July 20, 2022
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Luciana Diniz Nagem Janot Matos

PhD

Hospital Israelita Albert Einstein

Eligibility Criteria

Inclusion Criteria

  • Elderly of both sexes, over 65 years old

Exclusion Criteria

  • Mini Mental Test \<24
  • Morse ≥ 51
  • Clinical instability, according to medical assessment • Structural heart disease, with ejection fraction \<50% and chronic lung diseases with FEV1 \<50% predicted,
  • Neurological, orthopedic, or neuromuscular diseases that prevent the performance of evaluations
  • Smokers or ex-smokers \<5 years

Outcomes

Primary Outcomes

Peripheral muscle blood flow, gait speed and handgrip strength

Time Frame: Day 1

Check if there is a correlation between peripheral muscle blood flow, gait speed and handgrip strength and if this association is mediated by inspiratory muscle strength.

Study Sites (1)

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