Study of the Relationship Between Respiratory Muscle Strenght, Peripheral Muscle Blood Flow and Gait Speed in the Elderly
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Peripheral muscle blood flow, gait speed and handgrip strength
研究概览
简要总结
The pourpose of this study is to verify if have relationship between respiratory muscle strenght, peripheral muscle blood flow and gait speed in the elderly.
详细描述
The hypothesis of this study is that elderly with inspiratory muscle weakness will present lower peripheral blood flow and consequently lower walking speed. The main aim of the study is to verify if the peripheral muscular blood flow in the elderly is different between patients with and without decrease in inspiratory muscle strength. As secondary objectives, it will be evaluated the correlation between inspiratory muscle strength and gait speed and quality of life, as well as gait speed and peripheral muscle blood flow. Fifty elderly patients of both sexes, over 65 years, from Vila Mariana Einstein Outpatient Clinic and Cora Residencial Senior, will be included to evaluate Maximum Inspiratory Pressure (Pimáx), Maximum Expiratory Pressure (Pemáx), Spirometry (FVC, PF, FEV1), 4.6m Walk Test, Quality of life for the elderly (WHOQOL old), Mini Mental Test, Body Mass Index (BMI) and peripheral muscle blood flow by venous occlusion plethysmography.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 65 Years 至 100 Years(Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Elderly of both sexes, over 65 years old
排除标准
- •Mini Mental Test <24
- •Morse ≥ 51
- •Clinical instability, according to medical assessment • Structural heart disease, with ejection fraction <50% and chronic lung diseases with FEV1 <50% predicted,
- •Neurological, orthopedic, or neuromuscular diseases that prevent the performance of evaluations
- •Smokers or ex-smokers <5 years
结局指标
主要结局
Peripheral muscle blood flow, gait speed and handgrip strength
时间窗: Day 1
Check if there is a correlation between peripheral muscle blood flow, gait speed and handgrip strength and if this association is mediated by inspiratory muscle strength.
次要结局
未报告次要终点
研究者
Luciana Diniz Nagem Janot Matos
PhD
Hospital Israelita Albert Einstein
