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THE EFFECTIVENESS OF CURCUMIN AND NON-CURCUMIN TOOTHPASTE FORMULATION ON GINGIVITIS AND PERIODONTITIS

Phase 4
Completed
Conditions
Health Condition 1: K053- Chronic periodontitisHealth Condition 2: Z789- Other specified health status
Registration Number
CTRI/2022/07/043703
Lead Sponsor
ARUMUGAM P M
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

•Patients aged between 25 - 60yrs.

•All subjects having gingivitis and periodontitis with a probing pocket depth (PPD) of >3 mm.

•All subjects should have at least 20 natural teeth.

•All subjects need to have a plaque index of greater than 2 as measured by the Turesky et al. (1970) modification of the Quigley & Hein plaque index (1962).

•All subjects need to be mentally stable.

•Those who provide written informed consent will be included in the study.

•No subjects should have undergone any dental treatment in the four-week period prior to the baseline examination.

Exclusion Criteria

•Those who are undergoing antibiotic or anti-inflammatory therapy or on medication for any underlying systemic disorders.

•History of periodontal therapy in the past 6 months.

•Inability to participate in the study for its entire duration.

•Subjects with gross oral pathology are excluded.

•Female subjects who are either pregnant or taking the contraceptive pill.

•Subjects who have a history of known sensitivity or oral mucosal tissue reactions to the toothpaste.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
reduction in overall bacterial load, bleeding on probing, plaque accumulation and periodontal pocketTimepoint: 7 months
Secondary Outcome Measures
NameTimeMethod
reduction in bleeding on probing, plaque accumulation and periodontal pocketTimepoint: 7 months
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