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临床试验/CTRI/2025/01/079628
CTRI/2025/01/079628尚未招募4 期

Comparative Clinical Study To Evalute The Efficacy Of Prachanna Followed By Guduchi Taila Shirobhyanga And Growth Factor Concentrate Therapy On Khalitya (Male Pattern Alopecia)

DEPARTMENT OF PG AND Ph D STUDIES IN SHALAKYA TANTRA1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年2月2日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
Asessing Hair Growth in Male Pattern hairloss

研究概览

简要总结

Kesha is the mala of asthi dhatu. It is originated from pitrujabhava during garbhavastha and also one amongst the factor for assessment of prakriti of a person, and beauty of an individual. The gradual loss of hair is referred as Khalitya. Prakupita Pitta combines along with Vata and takes Sthana samshraya in Romakupa and results in hairfall. Thereafter Shleshma along with Shonita obstructs the channel of Romakoopa leading to the stoppage of the regeneration of hair and this condition is known as Khalitya. The treatment modalities of Khalitya includes Shiro Abyanga, Prachanna, Lepa, Nasya and Shodhana chikitsa.

85% of men and 33% of women are affected with hair loss across the globe. Androgenic alopecia is the most common type of hair loss with prevalence of 95%. The proportion of men with moderate to extensive Male pattern hair loss was 42% at age of 18 to 49 years. Topical minoxidil, oral administration of finasteride and hair transplantation are the mode of treatment which are not free from side effects. GFC is one of the safe treatment protocol in present era for androgenic alopecia.

Pracchana is a type of shastrakruta raktamokshana which helps to remove the vitiated rakta and kapha dosha which obstructs the hair root, enhance the efficacy of absorption of taila, helps to improve the perifollicular vascularization and strengthens the hair follicle. Guduchi taila has kesha ropana property and Yashtimadhu & amalaki churna have keshya property.

With these facts, the present study has been taken to compare the efficacy of Prachanna followed by Guduchi taila Shirobhyanga with internal administration of Yashtyamalaki churna in study group with Growth Factor Concentration therapy along with internal administration of Yashtyamalaki churna of comparator group.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
Male

入选标准

  • Patients having the classical clinical features of Khalithya Patients who have Male pattern alopecia Norwood Hamilton Scale up to G3 vertex.

排除标准

  • Alopecia totalis Alopecia aerata Tinia capitis Aroomshika Patients suffering from systemic diseases like anemia cancer diabetic mellitus rheumatological disorders SLE Hypertension Patients with history of NSAIDs and Anti platelet drug within 120 hours of procedure and systemic corticosteroids within last 2 weeks Corticosteroid injection at treatment site within one-month Covid-19 Serology positive patients platelet dysfunction syndrome Thyroid disorders cardiac complaints Norwood Hamilton Scale from G5-G8 Local infection at sight of procedure, Hb-less than 10g/dl, platelet count less than 105000/ml Tobacco and alcohol use.

结局指标

主要结局

Asessing Hair Growth in Male Pattern hairloss

时间窗: 120 days

次要结局

  • Reduction hair folicles in male pattern hairloss(120 days)

研究者

发起方
DEPARTMENT OF PG AND Ph D STUDIES IN SHALAKYA TANTRA
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

DR SANDEEP M

Shree Jagadguru Gavisiddeshwara Ayurvedic Medical College Post Graduate Studies And Research Center

研究点 (1)

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