Permanent Supportive Housing Overdose Prevention-2 Study

Not Applicable

Not yet recruiting

• Conditions: Overdose; Substance Use

• Registration Number: NCT07214519
• Lead Sponsor: NYU Langone Health

Brief Summary

This community-partnered study examines a technical assistance intervention designed to help permanent supportive housing agencies implement evidence-based practices to prevent tenant overdose and improve tenant health.

Detailed Description

Homelessness and housing instability are strongly linked with overdose risk. Permanent supportive housing (PSH) -subsidized housing paired with supportive services-is a key strategy to end homelessness yet supportive housing tenants face high overdose risk due to a confluence of factors. This multi-sector, community-partnered, stepped wedge randomized controlled trial evaluates the impact of a technical assistance intervention designed to support supportive housing agencies in sustainably implementing evidence-based practices to reduce tenant overdose and improve tenant health more broadly. The technical assistance intervention will be delivered to supportive housing agencies in New Jersey and New York who are enrolled in the trial. Outcomes include PSH agency implementation of overdose prevention practices and downstream tenant overdose, substance use, and other health-related outcomes. Outcomes will be assessed using surveys, administrative data, and agency records.

Study Timeline

• Study First Submitted: 2025-09-24
• Status Verified: 2025-10
• Study First Submitted QC: 2025-10-08
• Last Update Submitted: 2025-10-08
• Study First Posted: 2025-10-09
• Last Update Posted: 2025-10-09
• Study Start: 2027-07-01
• Primary Completion: 2030-09-30
• Study Completion: 2031-03-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 2940

Inclusion Criteria

Supportive Housing Agencies/Individuals who Work at Supportive Housing Agencies:

• Serve at least 40 tenants in New York and/or New Jersey
• Have a significant concern for overdose (as demonstrated by past year tenant overdose)
• Be willing to complete all activities required for participation in the trial

Tenants who Live in Supportive Housing Agencies:

• Must live in an enrolled Supportive Housing Agency
• Must be 18 years and older

Exclusion Criteria

• See inclusion criteria.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Composite Score of Agency-Level Fidelity to Overdose Prevention Evidence-Based Practices	Baseline, Month 12 (End of Wave 1), Month 19 (End of Wave 2), Month 26 (End of Wave 3), Month 33 (End of Wave 4)	Fidelity will be measured as the extent to which an intervention is implemented as intended by researchers; the specific method of measurement will be determined during the trial's preparatory phase, in consultation with multiple stakeholders. The measurement will comprise a composite score of multiple measures.

Trial Locations

Locations (1)

NYU Langone Health; 🇺🇸 New York, New York, United States